1-hydroxy Ethyl Radical Induced Oxidation of Resveratrol: the Mechanistic Aspect

نویسنده

  • Shashi P. Shukla
چکیده

Here in this paper, we report the mechanism of the free radical induced oxidation of Resveratrol. Hydroxy cinnamic acid derivatives have been used to examine the effect of molecular structure in antioxidant action. In these molecules addition to several phenolic groups, a vinyl moiety is present in the side chain. This study reveals a direct attestation that the unsaturated functionality in these molecules plays a key role in their antioxidant action.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Ferulic acid ethyl ester protects neurons against amyloid beta- peptide(1-42)-induced oxidative stress and neurotoxicity: relationship to antioxidant activity.

Alzheimer's disease (AD) is neuropathologically characterized by depositions of extracellular amyloid and intracellular neurofibrillary tangles, associated with loss of neurons in the brain. Amyloid beta-peptide (Abeta) is the major component of senile plaques and is considered to have a causal role in the development and progress of AD. Several lines of evidence suggest that enhanced oxidative...

متن کامل

OH radical initiated oxidation of 1,3-butadiene: isomeric selective study of the dominant addition channel.

We report the first isomeric selective kinetic study of the dominant isomeric pathway in the OH initiated oxidation of 1,3-butadiene in the presence of O(2) and NO using the laser photolysis-laser induced fluorescence (LP-LIF) technique. The photodissociation of the precursor 2-iodo-but-3-en-1-ol results exclusively in the dominant OH-butadiene addition product, permitting important insight int...

متن کامل

Glycosylation of resveratrol protects it from enzymic oxidation.

Plant polyphenols, including dietary polyphenols such as resveratrol, are important components in the plant antioxidant and defence systems. They are also known to exert beneficial effects on human health through diet. As they are produced, these polyphenols may be subjected to deleterious enzymic oxidation by the plant polyphenol oxidases. They are generally synthesized as glycosides like 5,4'...

متن کامل

Inhibitory Effects of Resveratrol against Mitochondrial Toxicity Induced by Perfluorooctanoic Acid in Isolated Liver Mitochondria of Male Rats

 Background and purpose: Resveratrol (RSV) is a naturally polyphenolic compound found in grapes and other plant sources. It has potent free radical scavenger and antioxidative properties.The aim of this study was to evaluate the protective effect of resveratrol against Perfluorooctanoic acid (PFOA) induced mitochondrial toxicity in isolated liver mitochondria. Materials and methods: Mitochondr...

متن کامل

Antibacterial Activity of Onopordum espinae: Identification of Hispidulin and Dehydromelitensin-8-(4'-Hydroxy-Methacrylate)

Hexane, ethyl acetate and methanol extracts of Onopordum espinae leaves were investigated for their antibacterial activities against Bacillus cereus, Staphylococcus aureus, Enterococcus faecalis, Escherichia coli, Pseudomonas aeruginosa and Salmonella enteritidis. The in vitro antibacterial activity of Onopordum espinae extracts was qualitatively assessed by the diameter of inhibition zones (IZ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010